Both quantitative flow ratio (QFR) and fractional flow reserve derived from computed tomography (FFRCT) have shown significant correlations with invasive wire-based fractional flow reserve. However, the correlation between QFR and FFRCT is not fully investigated in patients with complex coronary artery disease (CAD). The aim of this study is to investigate the correlation and agreement between QFR and FFRCT in patients with de novo three-vessel disease and/or left main CAD.
Reference: Diagnostic concordance and discordance between angiography-based quantitative flow ratio and fractional flow reserve derived from computed tomography in complex coronary artery disease. Kawashima H, Kogame N, Ono M, Hara H, Takahashi K, Reiber JHC, Thomsen B, de Winter RJ, Tanaka K, La Meir M, de Mey J, Schneider U, Doenst T, Teichgräber U, Wijns W, Mushtaq S, Pompilio G, Bartorelli AL, Andreini D, Serruys PW, Onuma Y. J Cardiovasc Comput Tomogr. 2022 Feb 19:S1934-5925(22)00031-4