Evolution from mitral annular dysfunction to severe mitral regurgitation in Barlow's disease

Interact Cardiovasc Thorac Surg

29 Dicembre Dic 2020 3 months ago
  • Gripari P, Pepi M

Barlow's disease (BD) is characterized by thick, redundant mitral valve (MV) leaflets, which can lead to prolapse and significant mitral regurgitation (MR). MV annular abnormalities are also commonly observed and increasingly recognized as possible primary pathology, with leaflet thickening being secondary to increased stress on the MV apparatus. To provide more insights into this hypothesis, the evolution of MV abnormalities over time in patients with BD was assessed.

Reference

Hiemstra YL, Tomsic A, Gripari P, van Wijngaarden AL, van der Pas SL, Palmen M, Klautz RJM, Pepi M, Bax JJ, Delgado V, Marsan NA. Evolution from mitral annular dysfunction to severe mitral regurgitation in Barlow's disease. Interact Cardiovasc Thorac Surg 2020 Dec 26;ivaa304. doi: 10.1093/icvts/ivaa304.

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