Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a fast spreading disease with high morbidity and mortality. COVID-19 can contribute to severe myocardial injury, ultimately culminating in acute coronary syndromes (ACS) . Clinical features and outcomes of patients with SARS-CoV-2 associated ACS have not been elucidated, yet.
In a multicenter study, COVID-19 positive patients diagnosed with angiographically confirmed ACS between February 19 and April 9 2020 at 17 sites in Italy, Spain, and Switzerland were compared to COVID-19 negative ACS patients from the University Hospital Zurich. In addition, patients with ST-segment elevation (STE)-ACS COVID 19 positive vs. COVID-19 negative were compared as well as patients with non-ST-segment elevation (NSTE)-ACS COVID-19 positive vs. COVID-19 negative.
Cammann VL, Szawan KA, D'Ascenzo F, Gili S, Dreiding S, Würdinger M, Manka R, Stähli BE, Holy EW, Siegrist P, Jakob P, Meyer P, Iannaccone M, Di Simone E, Secco GG, Saccocci M, Bettari L, Ielasi A, Tespili M, Quadri G, Varbella F, Raposeiras-Roubin S, Abu-Assi E, Mancone M, Sardella G, Infusino F, Fedele F, Patti G, Mennuni M, Rognoni A, Bollati M, Olivotti L, Cordone S, Carugo S, Barbieri L, Gaido L, Giammaria M, Gambino A, D'Amico M, Galluzzo A, Ugo F, Trabattoni D, De Filippo O, De Ferrari GM, Vecchione C, Citro R, Ghadri JR, Templin C. Outcomes of acute coronary syndromes in coronavirus disease 2019. Clin Res Cardiol 2020 Sep 19.doi: 10.1007/s00392-020-01742-6