Anti-phospholipid antibody prevalence and association with subclinical atherosclerosis and atherothrombosis in the general population

International Journal of Cardiology

26 Novembre Nov 2019 17 days ago
  • Baldassarre D

We performed a cross-sectional study on 1712 randomly enrolled subjects from a Northern Italian city to investigate the presence of aPLs and the association with subclinical atherosclerosis (using the carotid artery intima media thickness measured as inter-adventitia common carotid artery diameters - ICCAD) and retrospectively collected CV factors and events (i.e. acute myocardial infarction, stroke, and peripheral obliterans arterial vasculopathy) using physician-assisted questionnaires. We tested serum IgG, IgM, and IgA anti-cardiolipin, anti-beta2glycoprotein I (aGPI), and anti-phosphatidylserine-prothrombin antibodies.

Reference

Selmi C, De Santis M, Battezzati PM, Generali E, Lari SA, Ceribelli A, Isailovic N, Zermiani P, Neidhöfer S, Matthias T, Scirè CA, Baldassarre D, Zuin M. Anti-phospholipid Antibody Prevalence and Association With Subclinical Atherosclerosis and Atherothrombosis in the General Population. Int J Cardiol 2019 Nov 5. pii: S0167-5273(19)32822-0. doi: 10.1016/j.ijcard.2019.10.042.

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