We performed a cross-sectional study on 1712 randomly enrolled subjects from a Northern Italian city to investigate the presence of aPLs and the association with subclinical atherosclerosis (using the carotid artery intima media thickness measured as inter-adventitia common carotid artery diameters - ICCAD) and retrospectively collected CV factors and events (i.e. acute myocardial infarction, stroke, and peripheral obliterans arterial vasculopathy) using physician-assisted questionnaires. We tested serum IgG, IgM, and IgA anti-cardiolipin, anti-beta2glycoprotein I (aGPI), and anti-phosphatidylserine-prothrombin antibodies.
Selmi C, De Santis M, Battezzati PM, Generali E, Lari SA, Ceribelli A, Isailovic N, Zermiani P, Neidhöfer S, Matthias T, Scirè CA, Baldassarre D, Zuin M. Anti-phospholipid Antibody Prevalence and Association With Subclinical Atherosclerosis and Atherothrombosis in the General Population. Int J Cardiol 2019 Nov 5. pii: S0167-5273(19)32822-0. doi: 10.1016/j.ijcard.2019.10.042.