Patients with diabetes mellitus (DM) have worse outcomes after percutaneous coronary intervention (PCI). Recent evidences suggest a differential impact of insulin-treated and non insulin-treated DM on prognosis. The Authors of this study evaluated the clinical outcome of diabetic patients after PCI with polymer-free biolimus-eluting stent from the RUDI-FREE Registry, investigating a possible different prognostic impact of insulin-treated and non insulin-treated DM.
According to the conclusions, patients with DM had a higher risk of target lesion failure (TLF; composite of cardiac death, target vessel myocardial infarction, target lesion revascularization) compared with non diabetics. Nonetheless, the worse outcome of the diabetic population seems to be driven by the insulin-treated diabetic subpopulation.
This finding suggests a different risk profile of insulin-treated and non insulin-treated diabetic patients in the modern era of PCI.