Although acute coronary syndrome culprit lesions occur more frequently in the proximal coronary artery, whether the proximal clustering of high-risk plaque is reflected in earlier-stage atherosclerosis remains unclarified. We evaluated the longitudinal distribution of stable atherosclerotic lesions on coronary computed tomography angiography (CCTA) in 1,478 patients (mean age, 61 years; men, 58%) enrolled from a prospective multinational registry of consecutive patients undergoing serial CCTA.
Plaque Character and Progression According to the Location of Coronary Atherosclerotic Plaque. Bax AM, Yoon YE, Gianni U, Ma X, Lu Y, Lee BC, Goebel B, Han D, Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, Gonçalves PA, Pontone G, Shin S, Narula J, Lin FY, Shaw LJ, Chang HJ. Am J Cardiol. 2021 Aug 28:S0002-9149(21)00729-3. doi: 10.1016/j.amjcard.2021.07.040