No data on optimal management of patients with acute coronary syndromes (ACS) on long-term direct oral anticoagulants (DOACs) undergoing percutaneous coronary intervention (PCI) are available. Using the data of the Management of Antithrombotic TherApy in Patients with Chronic or DevelOping AtRial Fibrillation During Hospitalization for PCI study, we sought to compare the outcome of patients with ACS and atrial fibrillation (AF) who underwent PCI during uninterrupted DOAC (UDOAC group) and those who interrupted DOAC before PCI (IDOAC group).
Is percutaneous coronary intervention safe during uninterrupted direct oral anticoagulant therapy in patients with atrial fibrillation and acute coronary syndromes? De Luca L, Rubboli A, Bolognese L, Uguccioni M, Lucci D, Blengino S, Campodonico J, Meynet I, Brach Prever SM, Di Lenarda A, Gabrielli D, Gulizia MM; MATADOR-PCI Investigators. Open Heart. 2021 Jul;8(2):e001677. doi: 10.1136/openhrt-2021-001677.