Post-operative atrial fibrillation (POAF), defined as new-onset AF in the immediate period after surgery, is associated with poor adverse cardiovascular events and a higher risk of permanent AF. Mechanisms leading to POAF are not completely understood and epicardial adipose tissue (EAT) inflammation could be a potent trigger. Here, we aim at exploring the link between EAT-secreted interleukin (IL)-1β, atrial remodeling, and POAF in a population of coronary artery disease (CAD) patients.
Reference: Epicardial Adipose Tissue-Derived IL-1β Triggers Postoperative Atrial Fibrillation. Cabaro S, Conte M, Moschetta D, Petraglia L, Valerio V, Romano S, Di Tolla MF, Campana P, Comentale G, Pilato E, D'Esposito V, Di Mauro A, Cantile M, Poggio P, Parisi V, Leosco D, Formisano P. Front Cell Dev Biol. 2022 May 5;10:893729.