Quantification of myocardial blood flow (MBF) and functional assessment of coronary artery disease (CAD) can be achieved through stress myocardial computed tomography perfusion (stress-CTP). This requires an additional scan after the resting coronary computed tomography angiography (cCTA) and administration of an intravenous stressor. This complex protocol has limited reproducibility and non-negligible side effects for the patient. We aim to mitigate these drawbacks by proposing a computational model able to reproduce MBF maps.
Reference: Prediction of myocardial blood flow under stress conditions by means of a computational model. Di Gregorio S, Vergara C, Pelagi GM, Baggiano A, Zunino P, Guglielmo M, Fusini L, Muscogiuri G, Rossi A, Rabbat MG, Quarteroni A, Pontone G. Eur J Nucl Med Mol Imaging. 2022 May;49(6):1894-1905.