The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study

Biomedicines

7 April Apr 2021 3 months ago
  • Colombo GI, Bonomi A, Simonelli S, Amato M, Frigerio B, Ravani A, Sansaro D, Coggi D, MTremoli E, , Veglia F, Baldassarre D

The impact of cholesteryl ester transfer protein (CETP) on atherosclerosis is highly debated. This study aimed to investigate the associations between plasma CETP or CETP genotypes and carotid intima-media thickness (cIMT) and the influence of high-density lipoprotein cholesterol (HDL-C) on these associations.

Reference

Colombo GI, Bianconi V, Bonomi A, Simonelli S, Amato M, Frigerio B, Ravani A, Vitali C, Sansaro D, Coggi D, Mannarino MR, Savonen KP, Kurl S, Gigante B, Smit AJ, Giral P, Tremoli E, Calabresi L, Veglia F, Pirro M, Baldassarre D, On Behalf Of The Improve Study Group. The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study. Biomedicines 2021 Mar 11;9(3):286. doi: 10.3390/biomedicines9030286.

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