Common cardiovascular risk factors and in-hospital mortality in 3,894 patients with COVID-19: survival analysis and machine learning-based findings from the multicentre Italian CORIST Study

Nutr Metab Cardiovasc Dis

16 September Sep 2020 14 days ago
  • Agostoni P

There is poor knowledge on characteristics, comorbidities and laboratory measures associated with risk for adverse outcomes and in-hospital mortality in European Countries. The Authors aimed at identifying baseline characteristics predisposing COVID-19 patients to in-hospital death.

Based on machine learning and Cox survival analysis, a retrospective observational study on 3,894 patients with SARS-CoV-2 infection hospitalized from February 19th to May 23rd, 2020 and recruited in 30 clinical centres distributed throughout Italy, the paper concludes that the major predictors in that cohort of in-hospital death in patients with COVID-19 were: impaired renal function, elevated C-reactive protein and advanced age.


Reference
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