As pulmonary diffusing capacity is related to mortality risk and prognosis in patients with heart failure (HF), it is measured frequently. As such, it would be essential to know the week-to-week variability (reproducibility) of pulmonary diffusing capacity for carbon monoxide (DLCO) and nitric oxide (DLNO). This variability would let clinicians understand what a clinically measurable change in DLCO and DLNO would be in these patients.
Magini A, Contini M, Spadafora E, Apostolo A, Salvioni E, Barbieri S, Sciomer S, Andreini D, Veglia F, Zavorsky GS, Agostoni P. Variability in pulmonary diffusing capacity in heart failure. Respir Physiol Neurobiol 2020 Jun 5;103473. doi: 10.1016/j.resp.2020.103473.