G-CSF for Extensive STEMI: Results from the STEM-AMI OUTCOME CMR Substudy

Circulation Research

3 June Jun 2019 22 days ago
  • Pontone G, Bassetti B, Campodonico J, Guglielmo M, Muscogiuri G, Baggiano A, Colombo GI, Pompilio G

The STEM-AMI OUTCOME Cardiac Magnetic Resonance (CMR) Substudy was adequately powered to evaluate, in a population showing LV ejection fraction (LVEF){less than or equal to}45% after PCI for extensive STEMI, the effects of early administration of G-CSF in terms of LV remodeling and function, infarct size assessed by late gadolinium enhancement (LGE), and myocardial strain.

Reference

Achilli F, Pontone G, Bassetti B, Squadroni L, Campodonico J, Corrada E, Facchini C, Mircoli L, Esposito G, Scarpa D, Pidello S, Righetti S, Di Gennaro F, Guglielmo M, Muscogiuri G, Baggiano A, Limido A, Lenatti L, Di Tano G, Malafronte C, Soffici F, Ceseri M, Maggiolini S, Colombo GI, Pompilio G. G-CSF for Extensive STEMI: Results from the STEM-AMI OUTCOME CMR Substudy. Circ Res 2019 May 29. doi: 10.1161/CIRCRESAHA.118.314617

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