Predictive Value of Coronary Artery Calcium Scoring for Major Adverse Cardiac Events According to Renal Function

The prognostic performance of coronary artery calcium score (CACS) for predicting adverse outcomes in patients with decreased renal function remains unclear. The Authors aimed to examine whether CACS improves risk stratification by demonstrating incremental value beyond a traditional risk score according to renal function status.

In fact, the study shows that calcium score improved risk stratification and provided incremental value beyond Framingham 10-year risk score for predicting Major Adverse Cardiac Events, irrespective of estimated glomerular filtration rate.

Reference

1. Lee JH, Rizvi A, Hartaigh BÓ, Han D, Park MW, Roudsari HM, Stuijfzand WJ, Gransar H, Lu Y, Callister TQ, Berman DS, DeLago A, Hadamitzky M, Hausleiter J, Al-Mallah MH, Budoff MJ, Kaufmann PA, Raff GL, Chinnaiyan K, Cademartiri F, Maffei E, Villines TC, Kim YJ, Leipsic J, Feuchtner G, Pontone G, Andreini D, Marques H, de Araújo Gonçalves P, Rubinshtein R, Achenbach S, Shaw LJ, Chow BJW, Cury RC, Bax JJ, Chang HJ, Jones EC, Lin FY, Min JK, Peña JM. The Predictive Value of Coronary Artery Calcium Scoring for Major Adverse Cardiac Events According to Renal Function (from the Coronary Computed Tomography Angiography Evaluation for Clinical Outcomes: An International Multicenter [CONFIRM] Registry). Am J Cardiol 2019 Feb 10. pii: S0002-9149(19)30188-2. doi: 10.1016/j.amjcard.2019.01.055. [Epub ahead of print] Go to PubMed