A proteomic approach to identify novel disease biomarkers in LCAT deficiency

Journal of Proteomics

14 December Dec 2018 one month ago
  • Banfi C

This investigation defines the effects of LCAT deficiency on the level of the major plasma proteins in homozygous and heterozygous carriers. Increase for some proteins, with different function, together with a drop for haptoglobin, and specifically for haptoglobin beta chains, are reported for the first time as part of a coherent signature.

Reference

Simonelli S, Ossoli A, Banfi C, Pavanello C, Calabresi L, Gianazza E. A proteomic approach to identify novel disease biomarkers in LCAT deficiency. J Proteomics 2018 Dec 6. pii: S1874-3919(18)30427-5. doi: 10.1016/j.jprot.2018.12.005. [Epub ahead of print]

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