Adherence to the current guidelines on the early discontinuation of P2Y12 receptor antagonists is of utmost importance to reduce excessive bleeding and early mortality after CABG. Inter-institutional variation should be considered for a correct interpretation of the results in multicentre studies evaluating perioperative bleeding and use of blood products.
Biancari F, Mariscalco G, Gherli R, Reichart D, Onorati F, Faggian G, Franzese I, Santarpino G, Fischlein T, Rubino AS, Maselli D, Nardella S, Salsano A, Nicolini F, Zanobini M, Saccocci M, Ruggieri VG, Bounader K, Perrotti A, Rosato S, D'Errigo P, D'Andrea V, De Feo M, Tauriainen T, Gatti G, Dalén M. Variation in Preoperative Antithrombotic Strategy, Severe Bleeding and Use of Blood Products in Coronary Artery Bypass Grafting: Results from the Multicenter E-CABG Registry. Eur Heart J Qual Care Clin Outcomes 2018 Jun 23. doi: 10.1093/ehjqcco/qcy027. [Epub ahead of print]