Bone marrow ageing: implication for cell therapy with EPCs

Mechanisms of Ageing and Development

15 April Apr 2016 10 years ago
  • Zanobini 2

    Marco Zanobini

    EQUIPE MEMBER Mini- Invasive and Endoscopic Cardiovascular Surgery

    EQUIPE MEMBER Department of Cardiovascular Surgery

  • Erica Rurali, Beatrice Bassetti, Gianluca Perrucci, Elisa Gambini

In this review, we discussed the age-related changes of bone marrow (BM) and endothelial progenitor cells (EPCs) and their implication for cardiovascular cell-therapies and we examined alternative approaches under investigation to enhance EPC potency.

Reference: Rurali E, Bassetti B, Perrucci GL, Zanobini M, Malafronte C, Achilli F, Gambini E. BM ageing: implication for cell therapy with EPCs. Mech Ageing Dev 2016 [Epub ahead of print]

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