Bone Good to the Heart: Bone Marrow Cell Characteristics and Cardiac Repair After STEMI in the CCTRN TIME Cohort

Circ Res. 2015 Jan 2;116(1):16-18

14 January Jan 2015 11 years ago
  • Picozza M, Pompilio G, Capogrossi MC
An editorial discusses the implications of a paper of Shutt et al, that explores the characteristics of resident bone marrow cells (BMC) in patients enrolled in the Timing In Myocardial infarction Evaluation (TIME) clinical trial, in search of cellular correlates of reduction of the infarcted area 6 months after acute myocardial infarction (MI)
The central hypothesis is that endogenous BM properties could affect the clinical outcome. They found both phenotypic and biological BMC correlates of infarct size reduction, and the emerging picture is quite interesting.

Go to full text