Surfactant-Derived Proteins as Markers of Alveolar Membrane Damage in Heart Failure

PLoS One

22 December Dec 2014 11 years ago
  • Gargiulo P, Banfi C, Ghilardi S, Magrì D, Giovannardi M, Bonomi A, Salvioni E, Battaia E, Filardi PP, Tremoli E, Agostoni P
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In heart failure (HF) alveolar-capillary membrane is abnormal. Surfactant-derived proteins (SPs) and plasma receptor for advanced-glycation-end-products (RAGE) have been proposed as lung damage markers. Immature SP-B is the most reliable biological marker of alveolar-capillary membrane function in HF.