Gender and Acetazolamide Effects on Chemoreflex and Periodic Breathing During Sleep at Altitude

Chest

8 October Oct 2014 11 years ago
  • Caravita S, Faini A, Lombardi C, Valentini M, Gregorini F, Rossi J, Meriggi P, Di Rienzo M, Bilo G, Agostoni P, Parati G
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The greater severity of periodic breathing during sleep displayed by males at altitude could be attributed to their increased hypoxic chemosensitivity. Acetazolamide counteracted the occurrence of periodic breathing at altitude in both genders, modifying the apneic threshold and improving oxygenation.