P703NO synthetic pathway and oxidative stress in microvascular angina: assessment in red blood cells and plasma

A decreased nitric oxide (NO) bioavailability and an increased oxidative stress play a pivotal role in different cardiovascular pathologies. Recent studies have shown that red blood cells (RBCs) participate in NO formation in the bloodstream. The aim of this study was to outline the metabolic profile of L-arginine (Arg)/NO pathway and of oxidative stress status in RBCs and in plasma of patients with microvascular angina, investigating similarities and differences with respect to coronary artery disease  patients or healthy controls.

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