In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia

Thromb Haemost

2 April Apr 2014 12 years ago
  • Cavalca V, Rocca B, Squellerio I, Dragani A, Veglia F, Pagliaccia F, Porro B, Barbieri SS, Tremoli E, Patrono C
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In vivo prostacyclin biosynthesis in aspirin-treated essential thrombocythaemia patients appears unrelated to platelet thromboxane A2 biosynthesis, and not affected by an improved aspirin regimen, demonstrating its vascular safety for future trials.