Clinical Research - Critical Cardiology

Director Piergiuseppe Agostoni

Director: Piergiuseppe Agostoni

In the last 20 years, research performed in the Unit has allowed significant advances with important implications in the clinical field. The major research topics include:

  • Cardiopulmonary interactions in heart failure patients;
  • Beta-blockers influence on exercise performance in heart failure patients;
  • Adaptation to high altitude;
  • Gas exchange in heart failure;
  • Non invasive cardiac output determination during exercise;
  • The role of cardiopulmonary exercise testing in heart failure patients and management of heart failure in the new era: the role of scores;
  • The role of cardiopulmonary exercise testing in the clinical management of patients affected by pulmonary arterial hypertension;
  • The role of plasma SPB and RAGE as markers of lung injury;
  • Prognosis in heart failure in the era of β-blockers: role of severe exercise intolerance assessed by peak oxygen consumption; a finding from the MECKI database;
  • Ominous prognostic value of indeterminable anaerobic threshold in heart failure; a finding from the MECKI database;
  • Cardiopulmonary exercise testing and risk in heart failure: gender alone does not affect survival; a finding from the MECKI database;
  • Prognostic role of atrial fibrillation in patients affected by chronic heart failure; data from the MECKI score research group;
  • Exercise tolerance can explain the obesity paradox in patients with systolic heart failure; data from the MECKI score research group;
  • Multiparametric comparison of CARvedilol, vs. NEbivolol, vs. BIsoprolol in moderate heart failure: the CARNEBI trial;
  • Exercise performance in patient with Chronic Heart failure with Jarvik Device.

Mecki Score: Metabolic Exercise Cardiac Kidney Index

The Mecki Score is an instrument for calculating the risk of chronic systolic heart failure reserved exclusively for clinical use by physicians. → Go to the Mecki Score


See more in the Scientific Report