Clinical Research - Critical Cardiology
Director Piergiuseppe Agostoni
In the last 20 years, research performed in the Unit has allowed significant advances with important implications in the clinical field. The major research topics include:
- Cardiopulmonary interactions in heart failure patients;
- Beta-blockers influence on exercise performance in heart failure patients;
- Adaptation to high altitude;
- Gas exchange in heart failure;
- Non invasive cardiac output determination during exercise;
- The role of cardiopulmonary exercise testing in heart failure patients and management of heart failure in the new era: the role of scores;
- The role of cardiopulmonary exercise testing in the clinical management of patients affected by pulmonary arterial hypertension;
- The role of plasma SPB and RAGE as markers of lung injury;
- Prognosis in heart failure in the era of β-blockers: role of severe exercise intolerance assessed by peak oxygen consumption; a finding from the MECKI database;
- Ominous prognostic value of indeterminable anaerobic threshold in heart failure; a finding from the MECKI database;
- Cardiopulmonary exercise testing and risk in heart failure: gender alone does not affect survival; a finding from the MECKI database;
- Prognostic role of atrial fibrillation in patients affected by chronic heart failure; data from the MECKI score research group;
- Exercise tolerance can explain the obesity paradox in patients with systolic heart failure; data from the MECKI score research group;
- Multiparametric comparison of CARvedilol, vs. NEbivolol, vs. BIsoprolol in moderate heart failure: the CARNEBI trial;
- Exercise performance in patient with Chronic Heart failure with Jarvik Device.
Mecki Score: Metabolic Exercise Cardiac Kidney Index
The Mecki Score is an instrument for calculating the risk of chronic systolic heart failure reserved exclusively for clinical use by physicians. → Go to the Mecki Score