Effects of hypobaric hypoxia exposure at high altitude on left ventricular twist in healthy subjects: data from HIGHCARE study on Mount Everest
Eur Heart J Cardiovasc Imaging. 2015 Jul 4.
6
July
Jul
2015
10 years ago
In the multicenter HIGHCARE study, aimed at exploring the effects of high altitude hypoxia on multiple biological variables and their modulation by an angiotensin receptor blocker, the Authors addressed the effects of hypobaric hypoxia on both systolic and diastolic left ventricular geometry and function, focusing on echocardiographic assessment of left ventricle twist to indirectly examine subendocardial left ventricular systolic function.
The study, for the first time, demonstrates an increase in left ventricular twist at high altitude (Mount Everest base camp, 5400 m altitude) in healthy subjects exposed to high altitude hypoxia, suggesting the occurrence of subendocardial systolic dysfunction in such condition.
Go to NCBI abstract
The study, for the first time, demonstrates an increase in left ventricular twist at high altitude (Mount Everest base camp, 5400 m altitude) in healthy subjects exposed to high altitude hypoxia, suggesting the occurrence of subendocardial systolic dysfunction in such condition.
Go to NCBI abstract