Haemostatic and fibrinolytic changes in obese subjects undergoing bariatric surgery: the effect of different surgical procedures
Blood Transfus. 2014 Dec 16:1-6.
7
January
Jan
2015
11 years ago
Little is known about effects of different bariatric surgery procedures on haemostatic and fibrinolytic parameters.
In a total of 77 GBP (Gastric Bypass) and 79 SG (sleeve gastrectomy) subjects that completed the study, levels of haemostatic factors (FII, FVII, FVIII, FIX, FX, vWF, fibrinogen), fibrinolytic variables (PAI-1, t-PA and D-dimer) and natural anticoagulants (AT, protein C and protein S) were evaluated before and 2 months after surgery.
Gastric bypass is associated with an increased risk of post-operative deficiency in some vitamin K-dependent coagulation factors. Whereas such deficiency is too weak to cause bleeding, it is significant enough to increase the risk of thrombosis.
Go to NCBI abstract
In a total of 77 GBP (Gastric Bypass) and 79 SG (sleeve gastrectomy) subjects that completed the study, levels of haemostatic factors (FII, FVII, FVIII, FIX, FX, vWF, fibrinogen), fibrinolytic variables (PAI-1, t-PA and D-dimer) and natural anticoagulants (AT, protein C and protein S) were evaluated before and 2 months after surgery.
Gastric bypass is associated with an increased risk of post-operative deficiency in some vitamin K-dependent coagulation factors. Whereas such deficiency is too weak to cause bleeding, it is significant enough to increase the risk of thrombosis.
Go to NCBI abstract