You care better where you do Research

Research activities at Centro Cardiologico Monzino

Centro Cardiologico Monzino, as an IRCCS (Scientific Institute for Research, Hospitalization and Healthcare), is dedicated to cardiovascular scientific research and integrates clinical research with basic science research. Research programs are designed to facilitate the translation of laboratory studies on cellular systems and animal models into new diagnostic and therapeutic approaches for patients. Within this framework, our patients can play an active role through the Scientific Research Participation Agreement.

Monzino’s scientific output (in terms of articles published in peer-reviewed journals) is entirely focused on the cardiovascular field, ranging from clinical and interventional cardiology to vascular surgery, with particular emphasis on innovative imaging techniques and the development of biomarkers for identifying high-risk patients.

Monzino Cardiovascular Research in Numbers (2024 data)

• 14 Research Units
• 6 Core Facilities
• 111 Researchers
• 300 scientific publications in 2024 in national and international peer-reviewed journals (total 2024 Impact Factor generated: 2,264)
• 165 active clinical studies, including 45 newly initiated studies, with more than 3,100 enrolled patients.

Research Areas at Centro Cardiologico Monzino

BASIC RESEARCH

• Cardio-Oncology and Vascular Biology
• Molecular Mechanisms of Cardiovascular Remodeling
• Cardiac Development and Regeneration

TRANSLATIONAL RESEARCH

• Molecular Biology of Thrombosis in Cardiovascular Diseases
• Applied Biotechnologies in Cardiovascular Inflammation
• Inherited Cardiomyopathies
• Neuro-Cardiovascular Axis
• Cardiovascular Genetics
• Cardiovascular Tissue Engineering
• Cardiovascular Aging

CARDIOMETABOLISM & PREVENTION

• Arterial Morphology and Function
• Diabetology, Endocrinology and Metabolic Diseases (Clinical Research and Lipid Clinic)
• Cardiovascular Epigenetics
• Atherosclerosis Prevention

CORE FACILITIES

• Preclinical Disease Models
• iPSC Facility: Cardiac Modeling and Functional Assessment
• Bioinformatics & Artificial Intelligence
• Biostatistics & Clinical Data Platform

RESEARCH UNITS AND FACILITIES

• Functional Proteomics, Metabolomics and Network Analysis
• Functional Genomics

CLINICAL RESEARCH

• Arrhythmology
• Critical Care Cardiology
• Interventional Cardiology
• Cardiovascular Surgery
• Cardiovascular Imaging

Prof. Giulio Pompilio, Scientific Director of Monzino

“The research activities carried out at Centro Cardiologico Monzino are wide-ranging and multidisciplinary. They involve both physicians and dedicated researchers, including biologists, pharmacologists, and engineers. Research programs focus on the primary and secondary prevention of cardiovascular diseases, as well as the treatment and management of acute ischemic heart conditions (such as myocardial infarction), cardiac rhythm disorders (such as atrial fibrillation), and diseases requiring surgical intervention, including valvular heart disease and aortic disorders.

Within this framework, Monzino is engaged in innovative research in the fields of diagnostic imaging, genetics, and proteomics, always with the goal of translating research findings into clinical practice and making them available to patients as quickly as possible.”

Prof. Giulio Pompilio
Scientific Director, Centro Cardiologico Monzino