The early detection of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) is an unmet clinical need. ProEnkephalin (PENK) might improve the early detection of AKI.
Breidthardt T, Jaeger C, Christ A, Klima T, Mosimann T, Twerenbold R, Boeddinghaus J, Nestelberger T, Badertscher P, Struck J, Bergmann A, Hartmann O, Kalbermatter S, Marenzi G, Mueller C. Proenkephalin for the Early Detection of Acute Kidney Injury in Hospitalized Patients with Chronic Kidney Disease. Eur J Clin Invest 2018 Jul 16:e12999. doi: 10.1111/eci.12999. [Epub ahead of print]