An Editorial comment on "Physiological dead space and arterial carbon dioxide contributions to exercise ventilatory ineffciency in patients with reduced or preserved ejection fraction heart failure", by E.H. Van Iterson et al., published in the same issue of the European Journal of Heart Failure.
According to the Authors of the comment, evidence provided by Van Iterson et al. refreshes some knowledge on the ventilatory mediators of exercise intolerance and remarkably enriches the picture, especially prospecting for new insights on patients with HFpEF. Findings support the hypothesis that HFpEF and HFrEF may be two distinct entities also in terms of ventilatory response to physical challenge. The roadmap of HFpEF phenotyping is intriguingly moving forward, hopefully in the right direction.
- Agostoni P, Guazzi M. Exercise ventilatory inefficiency in heart failure: some fresh news into the roadmap of heart failure with preserved ejection fraction phenotyping. Eur J Heart Fail 2017 Oct 9. doi: 10.1002/ejhf.940. [Epub ahead of print] Go to the comment