Rationale and design of a global registry to evaluate real-world clinical outcomes in patients with AF and high risk of stroke treated with left atrial appendage occlusion using the AMPLATZER amulet device

Catheterization and Cardiovascular Interventions

13 Settembre Set 2017 8 days ago
  • Tondo C

There is an important need for prospective real-world clinical data of catheter-based LAA occlusion given the increasing application of this intervention. Aim of this paper is to describe the rationale and design of a global prospective registry on catheter-based left atrial appendage (LAA) occlusion using the second generation AMPLATZER Amulet LAA occlusion device and to provide a comprehensive perspective on available/ongoing registries for catheter-based LAA occlusion.

The Global Amplatzer Amulet LAA registry will collect safety and efficacy information on catheter-based LAA occlusion. The registry will expand our knowledge on peri-procedural and long-term outcome of catheter-based LAA occlusion using a second generation occlusion device. Characteristics of available and ongoing catheter-based LAA occlusion registries are described.

Reference

  • Hildick-Smith D, Diener HC, Schmidt B, Paul V, Settergren M, Teiger E, Camm J, Tondo C, Landmesser U. Rationale and design of a global registry to evaluate real-world clinical outcomes in patients with atrial fibrillation and high risk of stroke treated with left atrial appendage occlusion using the AMPLATZER amulet device-Perspective of available/ongoing registries of catheter-based LAA occlusion. Catheter Cardiovasc Interv 2017 Sep 1. doi: 10.1002/ccd.27252. [Epub ahead of print] Go to PubMed