Transcatheter Aortic Valve Implantation in Patients With Advanced Chronic Kidney Disease

American Journal of Cardiology

4 Aprile Apr 2017 6 months ago
  • Agrifoglio M

Advanced chronic kidney disease (CKD) is associated with poor outcomes in patients who underwent surgical aortic valve replacement, whereas its prognostic role in transcatheter aortic valve implantation (TAVI) remains unclear.

This study aimed to investigate outcomes in patients with advanced CKD who underwent TAVI. The Authors conclude that TAVI in predialytic or dialytic patients (i.e., S5) is independently associated with poor outcomes with more than double risk of death compared with patients with S4 renal function. Conversely, in severe CKD (i.e., S4) a rigorous risk stratification is required to avoid the risk of futility risk.

Reference

  • Conrotto F, Salizzoni S, Andreis A, D'Ascenzo F, D'Onofrio A, Agrifoglio M, Chieffo A, Colombo A, Rapetto F, Santini F, Tarantini G, Gabbieri D, Savini C, Immè S, Ribichini F, Valsecchi O, Aiello M, Lixi G, Iadanza A, Pompei E, Stolcova M, Ornaghi D, Minati A, Cassese M, Martinelli GL, Sbarra P, Agostinelli A, Audo A, Pieroni A, Fiorilli R, Gerosa G, Rinaldi M, Gaita F. Transcatheter Aortic Valve Implantation in Patients With Advanced Chronic Kidney Disease. Am J Cardiol. 2017 Feb 10. pii: S0002-9149(17)30141-8. doi: 10.1016/j.amjcard.2017.01.042. [Epub ahead of print] Go to PubMed