Vitamin D deficiency is a prevalent condition that occurs in about 30%-50% of the population. Clinical investigations have suggested that there is an association between hypovitaminosis D and acute myocardial infarction (AMI) or even increased morbidity and mortality in this clinical setting. Yet, despite observational and mechanistic data, interventional trials with supplementation of vitamin D are controversial.
In this review, the Authors discusse the evidence on the association between vitamin D deficiency and AMI, in terms of prevalence and prognostic impact, and the possible mechanisms mediating it. Further research in this direction is warranted and it is likely to open up new avenues for reducing the risk of AMI.
- Milazzo V, De Metrio M, Cosentino N, Marenzi G, Tremoli E. Vitamin D and acute myocardial infarction. World J Cardiol 2017; 9(1):14-20 Go to PubMed