Cardiac output (Q) is a key parameter in the assessment of cardiac function, its measurement being crucial for the diagnosis, treatment and prognostic evaluation of all heart diseases. Until recently, Q determination at peak exercise has been possible through invasive methods, so that normal values were obtained in studies based on small populations.
A new study was aimed to provide reference values for peak Q in the normal general population (500 normal subjects was studied) and to obtain a formula able to estimate peak exercise Q from measured peak oxygen uptake (VO2). The simultaneous measurement of Q and VO2 at peak exercise in a large sample of healthy subjects provided an equation to predict peak Q from peak VO2 values.
- Agostoni P, Vignati C, Gentile P, Boiti C, Farina S, Salvioni E, Mapelli M, Magrì D, Paolillo S, Corrieri N, Sinagra G, Cattadori G. Reference values for peak exercise cardiac output in healthy individuals. Chest 2017 Jan 17 [Epub ahead of print] Go to PubMed