Non-obstructive coronary artery disease (CAD) identified by coronary computed tomography angiography (CCTA) demonstrated prognostic value. CT-adapted Leaman score (CT-LeSc) showed to improve the prognostic stratification. Aim of this study was to evaluate the capability of CT-LeSc to assess long-term prognosis of patients with non-obstructive (CAD).
From 17 centers, the Authors enrolled 2,402 patients without prior CAD history who underwent CCTA that showed non-obstructive CAD and provided complete information on plaque composition. The study concludes that CT-LeSc is an independent predictor of major acute cardiac events, improving prognostic stratification of patients with non-obstructive CAD.
- Andreini D, Pontone G, Mushtaq S, Gransar H, Conte E, Bartorelli AL, Pepi M, Opolski MP, Ó Hartaigh B, Berman DS, Budoff MJ, Achenbach S, Al-Mallah M, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJ, Cury R, Delago A, Hadamitzky M, Hausleiter J, Feuchtner G, Kim YJ, Kaufmann PA, Leipsic J, Lin FY, Maffei E, Raff G, Shaw LJ, Villines TC, Dunning A, Marques H, Rubinshtein R, Hindoyan N, Gomez M, Min JK. Long-term prognostic impact of CT-Leaman score in patients with non-obstructive CAD: Results from the COronary CT Angiography EvaluatioN For Clinical Outcomes InteRnational Multicenter (CONFIRM) study. Int J Cardiol 2016 Dec 28 [Epub ahead of print] Go to PubMed