Additional value of inflammatory biomarkers and carotid artery disease in prediction of significant coronary artery disease as assessed by coronary computed tomography angiography

European Heart Journal of Cardiovascular Imaging

18 Ottobre Ott 2016 one month ago
  • Pontone G, Fusini L, Guglielmo M, Mushtaq S, Andreini D, Bartorelli AL, Pepi M

Aim of this paper is to evaluate the relationship between an incremental model, including cardiovascular risk factors, carotid disease and inflammatory biomarkers, to predict the presence of obstructive coronary artery disease (CAD).

Among asymptomatic intermediate-risk patients, the presence of increased IL-6 levels, in addition to traditional risk factors (male gender with diabetes) and carotid artery disease, predicts higher rates of obstructive CAD and it could be of help to identify which subset of asymptomatic patients could be referred to CCTA for screening.

Reference

  1. Guaricci AI, Pontone G, Fusini L, De Luca M, Cafarelli FP, Guglielmo M, Baggiano A, Beltrama V, Muscogiuri G, Mushtaq S, Conte E, Guglielmi G, Andreini D, Brunetti ND, Di Biase M, Bartorelli AL, Pepi M. Additional value of inflammatory biomarkers and carotid artery disease in prediction of significant coronary artery disease as assessed by coronary computed tomography angiography. Eur Heart J Cardiovasc Imaging 2016 Oct 14 [Epub ahead of print] Go to PubMed