Natriuretic peptide B plasma concentration increases in the first 12 h of pulmonary edema recovery

What about the quantitative meaning of BNP in the acute phase of pulmonary edema? (Int J Cardiol 2018 Mar 17)

27 March Mar 2018 2 months ago
  • Susini F, Assanelli E, Doria E, Morpurgo M, Brusoni D, Bonomi A, Barbieri S, Cabiati A, Salvini L, Chiodelli R, Loguercio M, Galli A, Agostoni P.

According to guidelines, single determination of B-type Natriuretic peptide (BNP) should be used for distinguishing between cardiac and non-cardiac acute dyspnea at the emergency room. BNP measurement is also recommended before hospital discharge in patients hospitalized for heart failure to assess prognosis and to evaluate treatment efficacy. In acute cardiogenic pulmonary edema, BNP is measured using a single BNP determination, but the temporal behavior of BNP during pulmonary edema recovery is unknown.

According to the Authors of a new study, in acute pulmonary edema, BNP increases up to 12 h after emergency admission regardless of dyspnea recovery time, making BNP quantitative meaning in the acute phase of pulmonary edema uncertain.

Reference

  • Susini F, Assanelli E, Doria E, Morpurgo M, Brusoni D, Bonomi A, Barbieri S, Cabiati A, Salvini L, Chiodelli R, Loguercio M, Galli A, Agostoni P. Natriuretic peptide B plasma concentration increases in the first 12 h of pulmonary edema recovery. Int J Cardiol 2018 Mar 17. pii: S0953-6205(18)30103-1. doi: 10.1016/j.ejim.2018.03.007. [Epub ahead of print] Go to PubMed