Preclinical data showed that overlapping (OVP) scaffolds might result in delayed healing and strut coverage compared to nonOVP scaffold segments. Furthermore, OVP in patients could result in increased periprocedure myocardial infarction (MI) rate secondary to side branch occlusion; however, little is known whether this may have an impact on long-term clinical outcomes.
In this stydy a low-to-moderate complex population treated with the ABSORB scaffold the OVP group showed a higher incidence of periprocedure MI with no immediate or long-term increase in cardiac death, TLR or ST.
- Costa JR Jr, Abizaid A, Bartorelli AL, Whitbourn R, Serruys PW, Smits PC; ABSORB EXTEND investigators. Two-year clinical outcomes of patients treated with overlapping absorb scaffolds: An analysis of the ABSORB EXTEND single-arm study. Catheter Cardiovasc Interv 2017 Oct 10. doi: 10.1002/ccd.27223. [Epub ahead of print] Go to PubMed