In this observational prospective study, the Authors assessed the role of clinical variables and circulating biomarkers in graft occlusion at 18 months to identify a signature for graft occlusion. In effect, D-dimer (as a biomarker associated with arterial and venous grafts occlusion) may help stratify patients at risk of graft failure and identify new molecular targets to prevent this complication.
- Parolari A, Cavallotti L, Andreini D, Myasoedova V, Banfi C, Camera M, Poggio P, Barili F, Pontone G, Mussoni L, Centenaro C, Alamanni F, Tremoli E; Coronary Bypass Grafting: Factors Related to Late Events and Graft Patency (CAGE) study investigators. D-dimer is associated with arterial and venous coronary artery bypass graft occlusion. J Thorac Cardiovasc Surg 7 Apr 27. pii: S0022-5223(17)30863-2. doi: 10.1016/j.jtcvs.2017.04.043. [Epub ahead of print] Go to PubMed