Association of non-alcoholic fatty liver disease and cardiometabolic risk factors with early atherosclerosis in an adult population in Southern Italy

Annali Istituto Superiore di Sanità

5 April Apr 2017 21 days ago
  • Baldassarre D, Amato M

The prevalence of risk factors for cardiovascular and metabolic diseases was investigated in an adult population of the city of Cittanova, Southern Italy. The study was conducted among 992 randomly selected adults aged 18-75 years, between April 2009 and January 2011.

Hypertension, central obesity, IFG, low HDL cholesterol, hypertriglyceridemia, MS, and increased carotid artery intima-media thickness (IMT) were significantly associated with NAFLD after adjustment for age and sex. With additional adjustment for body mass index (BMI), IMT and MS (depending on the prevalence ratio that was investigated), the positive association between the NAFLD and increased IMT lost statistical significance, while that with body mass index (BMI) and MS remained significant.

Reference

  • Caserta CA, Mele A, Surace P, Ferrigno L, Amante A, Messineo A, Vacalebre C, Amato F, Baldassarre D, Amato M, Marcucci F, Zuin M. Association of non-alcoholic fatty liver disease and cardiometabolic risk factors with early atherosclerosis in an adult population in Southern Italy. Ann Ist Super Sanita. 2017 Jan-Mar;53(1):77-81. doi: 10.4415/ANN_17_01_14. Go to PubMed