Lvad pump speed increase is associated with increased peak exercise cardiac output and vo2, postponed anaerobic threshold and improved ventilatory efficiency

International Journal of Cardiology

11 January Jan 2017 5 months ago
  • Vignati C, Apostolo A, Farina S, Sisillo E, Alamanni F, Paolillo S, Agostoni P

Peak exercise cardiac output (CO) increase is associated with an increase of peak oxygen uptake (VO2), provided that arteriovenous O2 difference [Δ(Ca-Cv)O2] does not decrease. At anaerobic threshold, VO2, is related to CO. We tested the hypothesis that, in heart failure (HF) patients with left ventricular assistance device (LVAD), an acute increase of CO obtained through changes in LVAD pump speed is associated with peak exercise and anaerobic threshold VO2 increase.

Reference
Vignati C, Apostolo A, Cattadori G, Farina S, Del Torto A, Scuri S, Gerosa G, Bottio T, Tarzia V, Bejko J, Sisillo E, Nicoli F, Sciomer S, Alamanni F, Paolillo S, Agostoni P. Lvad pump speed increase is associated with increased peak exercise cardiac output and vo2, postponed anaerobic threshold and improved ventilatory efficiency. Int J Cardiol 2016 [Epub ahead of print]

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