8-Hydroxy-2-deoxyguanosine levels and heart failure: A systematic review and meta-analysis of the literature

Nutrition, metabolism & cardiovascular diseases

11 January Jan 2017 3 months ago
  • Di Minno A, Turnu L, Porro B, Cavalca V, Tremoli E

The generation of reactive oxygen species (ROS) plays an important role in the etiology of several pathological conditions. High levels of 8-hydroxy-2-deoxyguanosine (8-OHdG), a biomarker of oxidative damage of DNA, have been found in patients with heart failure (HF). We performed a meta-analysis of the literature to investigate the association between 8-OHdG levels and HF.

Reference
Di Minno A, Turnu L, Porro B, Squellerio I, Cavalca V, Tremoli E, Di Minno MN. 8-Hydroxy-2-deoxyguanosine levels and heart failure: A systematic review and meta-analysis of the literature. Nutr Metab Cardiovasc Dis 2016 Nov 20 [Epub ahead of print]

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