Scar Homogenization Versus Limited-Substrate Ablation in Patients With Nonischemic Cardiomyopathy and Ventricular Tachycardia

Journal of the American College of Cardiololgy

2 November Nov 2016 10 months ago
  • Dello Russo A, Casella M, Tondo C

Scar homogenization improves long-term ventricular arrhythmia-free survival compared with standard limited-substrate ablation in patients with post-infarction ventricular tachycardia (VT). Whether such benefit extends to patients with nonischemic cardiomyopathy and scar-related VT is unclear. The aim of this study was to assess the long-term efficacy of an endoepicardial scar homogenization approach compared with standard ablation in this population.

In patients with dilated nonischemic cardiomyopathy, scar-related VT, and evidence of low-voltage regions on electroanatomic mapping, endoepicardial homogenization of the scar significantly increased freedom from any recurrent ventricular arrhythmia compared with a standard limited-substrate ablation, even if he success rate with this approach appeared to be lower than previously reported with ischemic cardiomyopathy

Reference

  1. Gökoğlan Y, Mohanty S, Gianni C, Santangeli P, Trivedi C, Güneş MF, Bai R, Al-Ahmad A, Gallinghouse GJ, Horton R, Hranitzky PM, Sanchez JE, Beheiry S, Hongo R, Lakkireddy D, Reddy M, Schweikert RA, Dello Russo A, Casella M, Tondo C, Burkhardt JD, Themistoclakis S, Di Biase L, Natale A. Scar Homogenization Versus Limited-Substrate Ablation in Patients With Nonischemic Cardiomyopathy and Ventricular Tachycardia. J Am Coll Cardiol 2016; 68(18):1990-1998. Go to PubMed