The presence of remodeled and mixed atherosclerotic plaques at coronary CT angiography predicts major cardiac adverse events - The CAFÉ-PIE Study

International Journal of Cardiology

16 May May 2016 6 months ago
  • Pontone G, Guglielmo M, Mushtaq S, Fusini L, Andreini D, Bartorelli A, Pepi M

It is still unclear how to exploit information made available by coronary computed tomography angiography (CCTA) on coronary artery disease (CAD) features in order to better predicting major adverse cardiac events (MACEs). Aim of this study was to validate the prognostic role of a comprehensive and simplified CT-derived score in 477 consecutive symptomatic patients without known CAD who underwent clinically-indicated CCTA for suspected CAD.

The Authors concluded that the use of an integrated score obtained with CCTA and based on the presence of remodeled and mixed atherosclerotic coronary plaques may improve MACE prediction in symptomatic patients at intermediate risk outweighing that provided by standard clinical and CCTA scores.

Reference

  • Guaricci AI, Pontone G, Brunetti ND, De Rosa F, Montrone D, Guglielmo M, Mushtaq S, Fusini L, Maffei E, Cademartiri F, Macarini L, Andreini D, Di Biase M, Bartorelli AL, Pepi M. The presence of remodeled and mixed atherosclerotic plaques at coronary ct angiography predicts major cardiac adverse events - The CAFÉ-PIE Study .Int J Cardiol 2016;215:325-331. Go to PubMed